Abstract Background Astrocytes (AC) are essential for brain homeostasis.Much data suggests that AC support and protect the vascular endothelium, but increasing evidence indicates that during injury conditions they may lose their supportive role resulting in endothelial cell activation and BBB disturbance.Understanding the triggers that flip this sw
Abstract Background Several health determinants are related to local conditions and prerequisites at community level.For this reason, strengthening community action has been one of five strategies implemented in health promotion since the end of the 1980s.Such action includes setting priorities, making decisions, planning strategies, and implementi
Recombinant adeno-associated virus (rAAV) has been developed as a successful vector for both basic research and human gene therapy.However, neutralizing antibodies (NAbs) against AAV capsids can abolish AAV infectivity on target cells, reducing the transduction efficacy.Absence of AAV NAb has become a prerequisite qualification for patients enrolle
INTRODUCTION: Patients with schizophrenia elicit cognitive decline from the early phase of the illness.Mismatch negativity (MMN) has been shown to be associated with cognitive function.We investigated the current source density of duration mismatch negativity (dMMN), by using low-resolution brain electromagnetic tomography (LORETA), and neuropsycho
This study investigated the potential of machine-learning-based stroke image reconstruction in capacitively coupled electrical impedance tomography.The quality of brain images reconstructed using the adversarial neural network (cGAN) was examined.The big data required for supervised network training were generated using a two-dimensional numerical